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Journal of Human Lactation, Vol. 18, No. 1, 66-68 (2002)
DOI: 10.1177/089033440201800112

Maternal Transplantation Medications During Breastfeeding

Noreen T. Coady, PharmD

Wyeth-Ayerst Pharmaceuticals in Randor, Pennsylvania; 9701 S. Natoma, Oaklawn, IL 60453, USA

Previously transplanted women have maintained successful pregnancies yet have been discouraged from breastfeeding. The American Academy of Pediatrics cautions against breastfeedingdue to documented presence of cyclosporine in breast milk and unknown long-term effects on nursinginf ants. Transplant centers, however, report mothers breastfeedingwith no measurable cyclosporine serum concentrations or untoward effects in their infants. Few data are available with regard to levels of other transplant medications in breast milk. Given the small number of published reports involvinglactatingw omen and relatively short follow-up of their infants, routine medication levels should be part of any screeningre gimen for such breastfed infants until further studies are available.

Key Words: breastfeeding • maternal transplantation • cyclosporine • immunosuppressive medications


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