Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

SAGETRACK

Sign In to gain access to subscriptions and/or personal tools.
Journal of Human Lactation
This Article
Right arrow Resumen
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Fernández, L.
Right arrow Articles by Rodríguez, J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fernández, L.
Right arrow Articles by Rodríguez, J. M.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Medline Plus Health Information
*Antibiotics
*High Risk Pregnancy
*Postpartum Care
*Staphylococcal Infections
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

The Bacteriocin Nisin, an Effective Agent for the Treatment of Staphylococcal Mastitis During Lactation

Leonides Fernández, PhD

Departamento de Nutrición, Bromatología y Tecnología de los Alimentos (NBTA), Universidad Complutense de Madrid (UCM), Spain

Susana Delgado, PhD

UCM

Helena Herrero, MSM

Association "Amamantar," Avilés, Spain

Antonio Maldonado, PhD

UCM

Juan M. Rodríguez, PhD

UCM, "Commensal Bacteria in the Perinatal Period" research group

Eight women with clinical signs of staphylococcal mastitis were randomly divided in 2 groups. A solution of the bacteriocin nisin (6 µg/mL) was applied to the nipple and mammary areola of those assigned to the nisin group for 2 weeks, and a similar preparation devoid of nisin was applied to the control group. On day 0, staphylococcal counts in breast milk of the nisin and control groups were similar (5.04 ± 0.19 and 4.88 ± 0.21 log10 CFU/mL, respectively). However, on day 14, the mean in the nisin group (3.22 ± 0.43 log10 CFU/mL) was statistically lower than that of the control group (5.01 ± 0.21 log 10 CFU/mL). No clinical signs of mastitis were observed among the women of the nisin group on day 14, whereas they persisted throughout the study in the women of the control group. In conclusion, nisin seems to be an efficient alternative to antibiotics for the treatment of staphylococcal mastitis. J Hum Lact. 24(3):311-316.

Key Words: nisin • mastitis • Staphylococcus • lactation

Journal of Human Lactation, Vol. 24, No. 3, 311-316 (2008)
DOI: 10.1177/0890334408317435
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?